The basic cause of acne is still unknown. It seems to be a multifactorial disease in which interaction of several factors play an important part in the pathogenesis. The primary event may be (a) obstruction of the sebaceous duct due to alteration in the pattern of keratinization within the follicle, (b) abnormal sebum production with excess quantities or altered composition or (c) increased bacterial colonization (proprionibacterium acnes and staphylococcus epidermi¬dis of pilosebaceous follicles which furnish the lipases responsible for hydrolysis of sebum triglycerides into free fatty acids. All three mechanisms may be involved. Obstruction of duct leads to forma¬tion of a comedone, the initial lesion of acne. A comedone can be located either in a closed follicle as a 'white head' consisting of lipid and keratin, or in an open follicle as 'black head' consisting of keratin and lipid with melanin deposition. The continual accumula¬tion of keratin and lipid may lead to rupture of the follicular wall and release of its contents into the surrounding dermis provoking an inflammatory tissue reaction.
Professional help will come in useful for more severe cases of acne. Experts will first observe the type of acne you have in order to recommend the best acne solutions. You may be prescribed astringents, creams or ointments which help reduce inflammation as well as keep your skin clean and dry.
Many of these cleansers act in almost exactly the same way as acne skin care products which have been formulated to limit the amount of oil or sebum forming in the pores. These types of products are reducing the chance of oil staying in the pores and aiding the growth of harmful bacteria which assists the formation of the skin condition.
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